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Dimitrios Nikolaou MD MRCOG

  • Consultant Gynaecologist, Specialist in Reproductive Medicine
  • and Surgery, Director, Ovarian Ageing and Fertility program,
  • Department of Obstetrics and Gynaecology, Chelsea and
  • Westminster Hospital, Imperial College School of Medicine,
  • London

My project here is to use the embodied and medicalized processes of childbirth as a lens through which we might more clearly see such traffic at work in a particular historical moment herbals best buy npxl 30 caps fast delivery. To put it simply quality herbals products pvt ltd order npxl 30 caps online, I will attempt to map out the trajectory of narratives working to produce knowledge about childbirth in the first decade of the twenty-first century in the United States herbals wholesale discount npxl online visa. Once I have drawn the basic contours of that map quest herbals order npxl 30caps fast delivery, I will focus in on smaller, more detailed regions, fleshing out the narratives particular to various discourse 18 communities and the contexts in which they have been used. In each chapter, I will be more specific about the methods I use for each of those discourse communities, especially how and why I chose certain texts. By unearthing the narratives circulating not just about birth, but also about the authority of professional medicine, the power of medical technology, and the role of scientific research in shaping medical practice and individuals relationships to health care, I intend to reframe discussions of birth through a more interdisciplinary lens. Moreover, I hope to use my analysis of childbirth discourses as a model to demonstrate that how science and medicine are articulated can have a weighty effect on material lives and to show that critiquing the way that articulation works can begin to trouble its persuasiveness. Though much of the work in feminist science studies and rhetorical studies of science 6 and medicine has focused on reproductive politics and technologies, few rhetoricians have turned their attention to the bodily process of childbirth and its scientific, medical, and cultural 7 trappings. I hope my project will fill that gap and bring this medically and technologically mediated event into larger conversations about the ways our cultural construction of biomedicine shapes our experiences of material reality. Social science literature, particularly sociology, anthropology, and history, has attended to the cultural meanings inscribed on the birthing body, especially since the 1970s. Much of this work focuses on the professionalization of obstetrics and the increased use of technological intervention in the birthing process. Wertz were among the first to produce a sustained historical critique of this kind, and their 1977 study, Lying-In: A History of Childbirth in America remains one of the most comprehensive narratives of how the shift from home to hospital came to be the norm. Their narrative works to revise what they call the ?success story of modern medicine to reveal a more complex web of power, economics, and a confluence of social forces that has resulted in a system where birth ?routinely requires the arts of medicine to overcome the processes of nature, often to the detriment of women (emphasis in original, xvi). Anthropologist Emily 8 For an overview of work they call the ?anthropology of birth, see Robbie Davis-Floyd and Carolyn F. Robbie Davis-Floyd, who has been writing about reproduction and medicine for nearly two decades, theorized what she called ?technocratic birth as an elaborate set of rituals, a ?rite of passage designed to communicate core cultural values to birthing women, especially that technology is superior and should be used to overcome the processes of nature, that their bodies are fundamentally flawed, and that physiological reproduction is inherently dangerous. Historian Judith Walzer Leavitt offered a revisionary history of the often-told story of medical men wresting control of birth from women by showing how women have always influenced the models of birth that rise to power. More recent work in the social sciences includes an ethnographic account of traditional African American midwifery in Virginia (G. Fraser), a history of anesthesia (Wolf), cultural analyses of specific obstetric practices like amniocentesis (Rapp) and fetal ultrasound (Taylor), and returns to earlier conceptions of power, knowledge, and medicine (Simonds, Rothman, and Norman; Davis-Floyd and Sargent). In the field of literary studies, scholarship particular to representations of childbirth is relatively sparse. Mothering has received a great deal of attention from feminist literary scholars, as has reproductive politics; far less attention has been paid to the maternal body. The unarticulated space of maternity exists largely because the maternal body occupies such a liminal space, 21 according to Kristeva: pregnancy is the ?threshold between culture and nature, unable to be subsumed by either the signified or the biological essence (182). The inability of existing discourses to speak to this condition are not inconsequential ?silence weighs heavily none the less on the corporeal and psychological suffering of childbirth and especially the self-sacrifice involved in becoming anonymous in order to pass on the social norm (183). As part of that project, she makes the case that dualism?especially the body/mind split?will never serve the interests of women, that we should be able to find ways to ?think through the body, without remaining trapped in patriarchal demands on it (284). In her attempt to make sense of her own bodily experience of maternity, she describes hospitalized childbirth as a metaphor for the oppression of women in general: ?No more devastating image could be invented for the bondage of woman: sheeted supine, drugged, her wrists strapped down and her legs in stirrups, at the very moment when she is bringing life into the world (171). Since Kristeva and Rich first articulated the need for more thinking about how to include the embodied experience of childbirth in feminist theorizing about maternity, relatively few scholars in literary studies have attended to that project. Part of the reason for that, according to some scholars, is that literature has often reproduced the cultural silences surrounding the birthing body of particular historical periods. Identifying the cultural forces and textual patterns that have 22 contributed to the persistence of such attitudes is one way some scholars have worked to reclaim the maternal body. Krista Ratcliffe, for instance, writes that the first step in liberating the maternal body from its marginalized position in discourse is to draw attention to the narrative silences surrounding birth, to dig into the ways that literary and cultural texts have evaded maternal experience. In literature, argues Ratcliffe, this silencing happens most often when male writers have ?remov[ed] birth from the physical realm and render[ed] it metaphorical (49) and when they have objectified birthing women and erased their perspective from the account (51). Patricia Yaeger also finds attending to the literary silences of birth an important component of establishing what she calls a ?poetics of birth. Another component of such a poetics would locate the spaces that unearth a ?reproductive unconscious, that point to reproductive anxiety or ?cultural contestation or struggle (267-68). Another way, and the one feminists interested in maternity have turned to most often, is to look to representations of birth by women writers. The edited collection, this Giving Birth, takes as its purpose this very recovery. This project will build on this small but rich body of scholarship on childbirth and extend the focus of analysis across disciplines and beyond the birthing room. As my review 24 shows, much of the scholarship specifically devoted to childbirth emerges out of a fairly static disciplinary boundary: the social sciences have produced research that has been primarily concerned with the material conditions of birth, while literary studies has been mostly concerned with the symbolic representation of childbirth; there has been little cross-over 9 between the two arenas. My project has been informed and enriched by much of this work, as it has taught us a great deal about the conditions and the representation of childbirth and medicine. Where I see my project intervening in this discussion is in connecting representation with its potential effects on material bodies, discourse with the knowledge it produces, and science and medicine with the narratives that give them meaning. A foundational premise for my study is that more purposeful interdisciplinarity can contribute to a fuller, richer understanding of childbirth and what it can mean for our engagement with medicine, science, and physiological human reproduction and can begin to unsettle the boundary between the ?real and the representational in order to bring them to bear on one another. Before I begin that project, of tracing the trajectory of childbirth and medicine through contemporary culture, I will briefly sketch the historical movements necessary to understand how we have arrived at the particular context of birth practices in the twenty-first century. Mazzoni and Adams also both use scientific and cultural discourses to illuminate their literary analyses in productive ways. However, this work is rarely taken up by scholars in other disciplines; though the individual texts themselves include some interdisciplinarity, the conversation, as I see it, has remained fairly enclosed within each disciplinary home. My hope is that by locating the conversation about childbirth squarely within medicine and science studies, rather than as a separate (and marginal) issue, those disciplinary boundaries will start to give way. Midwives attended 8% of all births, including certified nurse midwives attendance at hospital births, and traditional and nurse-midwives attendance at home and at freestanding birth centers (Martin et al. The vast majority of women also experience high rates of medical intervention, and many give birth by major abdominal surgery. Though the rates of preterm birth and low birthweight babies have slightly decreased in the last few years (Martin et al. The maternal and infant mortality rates, though relatively low compared to the rest of the world, are still higher than those in most industrialized countries (Wagner). Especially troubling is the racial disparity in birth outcome: African American women are four times more likely to die from childbirth-related causes than are white women in the United States and their babies are 26 twice as likely to die before their first birthdays (Hoyert 8-9). They also experience cesarean section at higher rates than any other racial or ethnic group and have much higher rates of preterm birth and low and very low birthweight babies (Martin et al. In general, birth is highly medically managed by the profession of obstetrics, but due to some of the concerning statistics listed above, a growing birth advocacy movement indicates increasing discontent with the current state of maternity care. Nonprofit organizations dedicated to reforming maternity care and hospital birth abound: the Center for Childbirth Choices, Childbirth Connection, the International Cesarean Awareness Network, as well as a grassroots campaign to legalize certified midwives in all fifty states. Additionally, blogs and social media devoted to childbirth reform have proliferated in the last few years, a phenomenon I will discuss in more detail in Chapter Five. The traditional story told in light of medical and scientific progress indicates that once upon a time, childbirth was a very dangerous event for women and babies, then doctors took over and began delivering babies in hospitals, and birth ceased to be a 10 risky affair. The logic implied by this narrative is that childbirth was dangerous because it lacked medical management, and obstetrical control and the hospital environment were the things that vastly improved birth outcomes. A more careful look at the big picture of history, however, has told a slightly different story. It was, without a doubt, far more dangerous than it is today; however, most historians and sociologists of medicine agree that the danger of mortality, for women and children, was caused by a range of factors, including very high fertility rates and a lack of safe, reliable contraception; the inability to diagnose or treat infection, especially with antibiotics; little knowledge about the physiological mechanisms and potential complications of birth; and poorer health in general, especially a lack of disease control for common causes of death like tuberculosis (Leavitt; Starr; Wertz and Wertz). Both groups of women experienced many physical complications as the result of years of continuous childbearing, including vaginal fistulas, incontinence, and prolapsed uteri, all of which contributed to even more painful and complicated deliveries (Leavitt 29-30). Though it is impossible to determine exactly how many pregnancies women endured or how many deaths resulted, the cultural attitudes towards the event of birth indicate that it was shrouded in the possibility of death, for mother or child. Leavitt writes that ?childbed deaths were so familiar to Americans, from the eighteenth century to the twentieth century, that fearful anticipation characterized the common and realistic attitude towards pregnancy (27). It is no wonder, then, that many women welcomed the possibility of scientific medicine and professional expertise to alleviate some of that anxiety. Until the nineteenth century, many of these women would have had little to no formal education and no access to formal midwifery training; their training in attending births would have been experiential (Rooks 20-21).

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The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis. The Incidence and Prevalence of Systemic Lupus Erythematosus in San 2136?2148 Francisco County, California: the California Lupus Surveillance Project. Prevalence and Incidence of Systemic Lupus Erythematosus in a Hospitalization rates and utilization among patients with rheumatoid arthritis: a Population-Based Registry of American Indian and Alaska Native People, 2007 population-based study from 1987 to 2012 in Olmsted County, Minnesota. The impact of menopause on functional status in women with systemic lupus erythematosus. Neuropsychiatric Events at the Time of Diagnosis of Systemic Lupus Erythematosus: an International Inception Cohort Study. Systemic Lupus International Collaborating Clinics, Prospective Singh S, Saxena R. Analysis of Neuropsychiatric Events in an International Disease Inception Cohort of Patients With Systemic Lupus Erythematosus. A Structured Literature Review of the Direct Costs of Adult Systemic Lupus Erythematosus in the U. The Frequency and Outcome of Lupus Nephritis: Results From an International Inception Cohort study. Population-Based Incidence and Prevalence of Systemic Lupus Erythematosis: the Michigan Lupus Epidemiology and Surveillance Program. Similarities and Differences Between Pediatric and Adult Patients With J Rheumoatology. Disease Outcomes and Care Fragmentation Among Patients With Systemic Lupus Erythematosus. Longitudinal Treatment Patterns and Associated Outcomes in Patients [Epub ahead of print] With Newly Diagnosed Systemic Lupus Erythematosus. Healthcare Utilization and Costs of Systemic Lupus Erythematosus in Endstage Renal Disease in Patients with Lupus Nephritis. Pediatric Systemic Lupus Erythematosus: More than a Positive Antinuclear 2002?2004: the Georgia Lupus Registry. The Lupus and Allied Diseases Association, the Lupus Foundation of America, and Yazdany J and Yelin E. Health Care Costs and Costs Associated With Changes in Work Productivity Among Persons With Systemic Lupus Erythematosus. Healthcare Costs of Pregnancy in Systemic Lupus Erythematosus: Retrospective Observational Analysis From a U. Brain Magnetic Resonance Imaging in Newly Diagnosed Systemic information/sjogrens-syndrome/neurologic-complications Lupus Erythematosus. Management of Cardiovascular Risk Factors in Patients With Systemic a large United States population highlight real-world health care burden and lack Lupus Erythematosus. With Psoriasis and Psoriatic Arthritis: Data From National Psoriasis Foundation Cochrane Database of Systematic Reviews. The Prevalence of Rheumatologist-Diagnosed Psoriatic Arthritis in Patients With Psoriasis in European/North American Dermatology Clinics. Economic Considerations of the Treatment of Ankylosing Clinical Depression in Psoriasis Patients: A Systematic Review and Meta-Analysis. Increased Burden of Infammation Over Time is Associated With the Extent Estimates From a Cross-sectional Survey. Is Ankylosing Spondylitis a Risk Factor for Cardiovascular Journal of the Medical Sciences. Effect of biologics on depressive symptoms in patients with psoriasis: a systematic review. Comparison of Health-related Quality of Life in Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis and Effects of Etanercept Treatment. High Prevalence of Psoriatic Arthritis in Patients With Severe 2012; 38(3): 441?476. Interactions of the Immune System With Skin and Bone Tissue in Psoriatic Arthritis: a Comprehensive Review. Sweeney S, Gupta R, Taylor G, et al: Total hip arthroplasty in ankylosing spondylitis: Outcome in 340 patients. Patient Perspectives in the Management of Psoriasis: Results School Impairment among Adolescents with Primary Pain Conditions, Juvenile From the Population-based Multinational Assessment of Psoriasis and Psoriatic Idiopathic Arthritis Pain, and Pain-Free Peers. Fatigue in Patients with Juvenile Idiopathic Arthritis: A Systematic Liu J-T, et al. The Outcomes of Juvenile Idiopathic Arthritis in Children immunological patterns of disease expression in a cohort of 56 patients. Incidence and prevalence of juvenile idiopathic arthritis among Clinical characteristics, disease activity and damage. Population-based Study of Outcomes of Patients with Juvenile systemic lupus erythematosus: a longitudinal study. Accessed on and juvenile chronic arthritis in a Chinese population: a nation-wide prospective 6. Depression and anxiety and their association with healthcare Patients with Juvenile Idiopathic Arthritis: the Pediatric Rheumatology International utilization in pediatric lupus and mixed connective tissue disease patients: a Trials Organization Multinational Quality of Life Cohort Study. Juvenile Idiopathic Arthritis: the Pediatric Rheumatology International Trials Available at: resources. Prevalence, Risk Factors, and Outcome of Uveitis in Juvenile Idiopathic Arthritis: A long-term follow-up study. Pediatric Lupus Are There Differences in Presentation, Genetics, Response to Therapy, Damage Accrual Compared to Adult Lupus? Determinants of Health-related Quality of Life in Children Newly Rheum Dis Clin North Am. Pediatric Systemic Lupus Erythematosus: More than a Positive Antinuclear Antibody. A comparison of the outcome of adolescent and adult-onset systemic lupus erythematosus. Damage Extent and Predictors in Adult and Juvenile Dermatomyositis and Polymyositis Using the Myositis Damage Index. Clinical and Immunologic Dermatoyositis: the Childhood Arthritis and Rheumatology Research Alliance Features of 153 Patients in an International Database. Extended report: cardiac dysfunction in juvenile dermatomyositis: a Panigada S, et al. Incidence of systemic connective tissue diseases in children: a nationwide prospective study in Finland. Mindfulness-based Stress Reduction for Adolescents with Functional serologic features, and survival in comparison with adult onset disease. Measures of Juvenile Fibromyalgia: Functional Disability Opinions in Rheumatology. In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of infammation: a Kashikar-Zuck, et al. Complete and Sustained Remission of Juvenile Dermatomyositis Kashikar-Zuck S, et al. 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Hygiene ?If the baby is not yet suckling well and long enough herbs used for protection npxl 30caps for sale,do whatever works better in your setting:Keep the baby longer at the breast herbs to lower blood pressure cheap 30 caps npxl visa. On the first day express breast milk General principles are found in the section on good care A1-A6 himalaya herbals india npxl 30 caps without prescription. Express breast milk?The mother needs clean containers to collect and store the milk vindhya herbals order npxl discount. To feed the baby if the baby issmall and too weak to suckle ?Wait until the baby is alert and opens mouth and eyes,or stimulate the baby lightly to awaken her/him. Inform the mother that the baby has difficulty initiating breathing and that you will help the baby to breathe. To relieve engorgement and to help baby to attachTo drain the breast when she has severe mastitis or abscesses. Ask the mother to repeat this process every 1-2 hours if the baby is very small(or every 2-3 hours if the baby is not very small). Introduce the suction tube 3cm into each nostril and suck while withdrawing until no mucus. If breathing less than 30 breaths per minute orsevere chest in-drawing: Open the airway >>>Continue alternating sides for at least 20-30 minutes. Express breast milk ?>>Squeeze bag attached to the mask with 2 fingers or whole hand,according to bag size,2 or 3 times. Hand express breast milk directly into the ?Explain to the mother and give supportive careRecord the event. The mother should:Measure the quantity of milk in the cup Quantity to feed by cup?Start with 80 ml/kg body weight per day for day 1. Feed for a longer time or feed more often Signs that baby is receiving ?infection. Baby gains at least 160g in the following weeks or a minimum 300g in the first month. Ask her to let you know if the local infection gets worse and to return to the clinic if possible. Follow up the baby every 2 weeks,or according to national guidelines,to assess weight gain. Every 2 weeks if replacement feeding orWhen the baby is brought for examination because not feeding well,or ill. They should not have any other food or drink Check that position and attachment are correct at the first feed. Support exclusive breastfeeding Teach correct positioning and attachment Keep the mother and baby together in bed or within easy reach. She should: > A baby needs to feed day and night, 8 or more times in 24 hours from birth. Wake the baby for feeding, even if she/he does not wake up alone, 2 hours after the last feed. If necessary, improve the milk flow (let the mother express a little breast milk before attaching the baby to the breast). To feed the baby if the baby is Wait until the baby is alert and opens mouth and eyes, or stimulate the baby lightly to awaken her/him. Increase total volume by 10-20 ml/kg per day, Measure the quantity of milk in the cup until baby takes 150 ml/kg/day. Signs that baby is receiving If mother does not express enough milk in the first few days, or if the mother cannot breastfeed at all, use one of the following feeding options: adequate amount of milk > donated heat-treated breast milk Baby is satisfied with the feed. Every 2 weeks if replacement feeding or 1 week Loss up to 10% treatment with isoniazid. First week No weight loss or total less than 10% Weekly until 4-6 weeks of age (reached term). Afterward daily gain in small babies at least 20 g Scale maintenance Daily/weekly weighing requires precise and accurate scale (10g increment): > Calibrate it daily according to instructions. Do not bind the breasts tightly as this may increase condition at least twice daily. Warmth is comfortable for some mothers, others prefer a cold compress to reduce milk if possible. It will If the baby does not have a mother be less than her baby would take and will not stimulate increased milk production. Some women use plant Give donated heat treated breast milk or home-based or commercial formula by cup. After bathing, dry immediately and If the mother cannot keep the baby skin-to-skin because of complications, wrap the baby in a clean, dry, thoroughly. If the room is not warm enough, always cover the baby with possible, day and night. Keep the baby warm If breathing or crying, stop ventilating Clamp and cut the cord if necessary. If chest is not rising: record the event on the referral form and labour record. Colours range from yellow (negative) through yellow-green andDip coated end of paper dipstick in urine sample. Let test tube sit 20 minutes to allow serum to separate (or centrifuge 3-5 minutes at 2. Weakly reactive(minimal clumping) Positive for syphilis Important: Several samples may be tested on one card. Colours range from yellow (negative) through yellow-green and green-blue for positive. Most test cards include negative and positive control circles for Explain procedure. Non-reactive (no clumping or only slight roughness) Negative for syphilis Let test tube sit 20 minutes to allow serum to separate (or centrifuge 3-5 minutes at 2. Weakly reactive (minimal clumping) Positive for syphilis Use sampling pipette to withdraw some of the serum. Take care not to include any red blood cells from the lower part of the separated sample. For a woman who prefers to deliver at home the following recommendations are provided for a clean home delivery to be reviewed during antenatal care visits. Delivery at home with an attendant partner and family on care during pregnancy, preparing a birth and >>>Check your health and the progress of the pregnancyHelp you make a birth planAnswer questions or concerns you may have If you have any of these signs,go to the health centre as soon as you can. Know the signs of labour >>20cm each to tie the cord,and clean cloths to cover the birth place. Prepare the home and the supplies indicated for a safe birth:>Have these supplies organized for a clean delivery: new razor blade,3 pieces of string aboutClean,warm birth place with fresh air and a source of light ?When the baby is born,place her/him on your abdomen/chest where it is warm and clean. Dry theCut the cord when it stops pulsating,using the disposable delivery kit,according to instructions. Care for yourself during pregnancy >Clean cloths:>>Clean warm blanket to cover youfor drying and wrapping the baby ?Wait for the placenta to deliver on its own. Care for yourself during pregnancy?Bring your home-based maternal record to every visit. Routine visits to the health centre >>>>Three bowls,two for washing and one for the placentaBuckets of clean water and soap for washing,for you and the skilled attendantPlastic for wrapping the placentaMeans to heat water and safer delivery at home baby after delivery, breastfeeding and care after an abortion. Eat more and healthier foods,including more fruits and vegetables,beans,meat,fish,eggs,cheese,milk. Go to the health centre?abdominal painfever as soon as possibleif any of the following signs: >Bucket for you to urinate in. Based on yourWhether in a hospital,health centre or at home,it is important to deliver with a skilled attendant. Avoid harmful practices ?Planning for delivery at homeWho will support you during labour and delivery? Planning for delivery at the hospital or health centre>Who will help to care for your home and other children while you are away? Organize the following:>Who will help you to care for your home and other children? A clean delivery kit which includes soap,a stick to clean under the nails,a new razor blade to cut ?Who will help you while you are away and care for your home and other children?

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Relationships with Parents and Siblings In early adulthood the parent-child relationship has to transition toward a relationship between two adults wicked herbals purchase cheap npxl line. One of the biggest challenges for parents herbalsondemandcom quality 30 caps npxl, especially during emerging adulthood herbals recalled purchase npxl amex, is coming to terms with the adult status of their children gayatri herbals discount 30caps npxl visa. Aquilino (2006) suggests that parents who are reluctant or unable to do so may hinder young adults identity development. This problem becomes more pronounced when young adults still reside with their parents. Arnett (2004) reported that leaving home often helped promote psychological growth and independence in early adulthood. Yet, there is little research on the nature of sibling relationships in adulthood (Aquilino, 2006). What is known is that the nature of these relationships change, as adults have a choice as to whether they will maintain a close bond and continue to be a part of the life of a sibling. Siblings must make the same reappraisal of each other as adults, as parents have to with their adult children. Research has shown a decline in the frequency of interactions between siblings during early adulthood, as presumably peers, romantic relationships, and children become more central to the lives of young adults. Aquilino (2006) suggests that the task in early adulthood may be to maintain enough of a bond so that there will be a foundation for this relationship in later life. Those who are successful can often move away from the ?older-younger sibling conflicts of childhood, toward a more equal relationship between two adults. Siblings that were close to each other in childhood are typically close in adulthood (Dunn, 1984, 2007), and in fact, it is unusual for siblings to develop closeness for the first time in adulthood. Intimate relationships are more difficult if one is still struggling with identity. Achieving a sense of identity is a life-long process, as there are periods of identity crisis and stability. These intimate relationships include acquaintanceships and friendships, but also the more important close relationships, which are the long-term romantic relationships that we develop with another person, for instance, in a marriage (Hendrick & Hendrick, 2000). Factors influencing Attraction Because most of us enter into a close relationship at some point, it Figure 7. A major interest of psychologists is the study of interpersonal attraction, or what makes people like, and even love, each other. Similarity: One important factor in attraction is a perceived similarity in values and beliefs between the partners (Davis & Rusbult, 2001). We can feel better about ourselves and our choice of activities if we see that our partner also enjoys doing the same things that we do. Having others like and believe in the same things we do makes us feel validated in our beliefs. This is referred to as consensual validation and is an important aspect of why we are attracted to others. Source: Self-Disclosure: Liking is also enhanced by self-disclosure, the tendency to communicate frequently, without fear of reprisal, and in an accepting and empathetic manner. Friends are friends because we can talk to them openly about our needs and goals and because they listen and respond to our needs (Reis & Aron, 2008). If we open up about our concerns that are important to us, we expect our partner to do the same in return. Proximity: Another important determinant of liking is proximity, or the extent to which people are physically near us. Research has found that we are more likely to develop friendships with people who are nearby, for instance, those who live in the same dorm that we do, and even with people who just happen to sit nearer to us in our classes (Back, Schmukle, & Egloff, 2008). Proximity has its effect on liking through the principle of mere exposure, which is the tendency to prefer stimuli (including, but not limited to people) that we have seen more frequently. The effect of mere exposure is powerful and occurs in a wide variety of situations. Infants tend to smile at a photograph of someone they have seen before more than they smile at a photograph of 280 someone they are seeing for the first time (Brooks-Gunn & Lewis, 1981), and people prefer side to-side reversed images of their own faces over their normal (nonreversed) face, whereas their friends prefer their normal face over the reversed one (Mita, Dermer, & Knight, 1977). This is expected on the basis of mere exposure, since people see their own faces primarily in mirrors, and thus are exposed to the reversed face more often. We have an initial fear of the unknown, but as things become familiar, they seem more similar and safer, and thus produce more positive affect and seem less threatening and dangerous (Harmon-Jones & Allen, 2001; Freitas, Azizian, Travers, & Berry, 2005). Familiar people become more likely to be seen as part of the ingroup rather than the outgroup, and this may lead us to like them more. Zebrowitz and her colleagues found that we like people of our own race in part because they are perceived as similar to us (Zebrowitz, Bornstad, & Lee, 2007). Friendships In our twenties, intimacy needs may be met in friendships rather than with partners. This is especially true in the United States today as many young adults postpone making long-term commitments to partners, either in marriage or in cohabitation. The kinds of friendships shared by women tend to differ from those shared by men (Tannen, 1990). Friendships between men are more likely to involve sharing information, providing solutions, or focusing on activities rather than discussion problems or emotions. Men tend to discuss opinions or factual information or spend time together in an activity of mutual interest. Friendships between women are more likely to focus on sharing weaknesses, emotions, or problems. Women talk about difficulties they are having in other relationships and express their sadness, frustrations, and joys. These differences in approaches lead to problems when men and women come together. She may want to vent about a problem she is having; he may want to provide a solution and move on to some activity. Friendships between men and women become more difficult because of the unspoken question about whether the friendships will lead to a romantic involvement. Consequently, friendships may diminish once a person has a partner or single friends may be replaced with couple friends. Love relationships vary depending on the presence or absence of each of these components. Passion refers to the intense, physical attraction partners feel toward one another. Intimacy involves the ability the share feelings, psychological closeness and personal thoughts with the other. Passion can be found in the early stages of a relationship, but intimacy takes time to develop because it is Source 281 based on knowledge of the partner. Once intimacy has been established, partners may resolve to stay in the relationship. Although many would agree that all three components are important to a relationship, many love relationships do not consist of all three. Liking: In this relationship, intimacy or knowledge of the other and a sense of closeness is present. They may feel that the other person knows them well and can be honest with them and let them know if they think the person is wrong. However, being told that your partner ?thinks of you as a friend can be a devastating blow if you are attracted to them and seeking a romantic involvement. A person who is infatuated finds it hard to think of anything but the other person. Infatuation is rather short-lived, however, lasting perhaps only a matter of months or as long as a year or so. It tends to be based on physical attraction and an image of what one ?thinks the other is all about. Fatuous Love: However, some people who have a strong physical attraction push for commitment early in the relationship. They focus on their intense physical attraction and yet one, or both, is also talking of making a lasting commitment. Sometimes this is out of a sense of insecurity and a desire to make sure the partner is locked into the relationship. Empty Love: this type of love may be found later in a relationship or in a relationship that was formed to meet needs other than intimacy or passion, including financial needs, childrearing assistance, or attaining/maintaining status. Here the partners are committed to staying in the relationship for the children, because of a religious conviction, or because there are no alternatives.

Colitis accompanied by anemia herbs de provence order generic npxl line, thrombo Pyloric stenosis classically presents between 3 and 6 weeks cytopenia quality herbals products pvt ltd cheap npxl 30caps on line, or renal insufciency (consistent with hemolytic 10 of age as nonbilious vomiting that rapidly progresses to uremic syndrome) should prompt a specifc investigation for frequent projectile vomiting herbals and anesthesia buy npxl 30caps on-line, ofen complicated by dehydration herbals names buy discount npxl 30 caps on line, Escherichia coli serotype 0157:H7. Food protein?induced enterocolitis syndrome and food protein 12 19 induced proctitis (milk protein sensitivity) typically present as a Approximately two thirds of Meckel diverticula occur as a history of bloody mucous stools and increasing stool frequency. The bleeding is due to ulceration from gastric mucosa con develop an identical clinical picture. Peutz-Jeghers syndrome is characterized by difuse intestinal If the perianal region is erythematous, obtain a culture for group hamartomas and hyperpigmented macules of the oral mucosa. Careful history-taking may narrow the or ischemia) and crying occur, accompanied initially by periods of diferential diagnosis and guide the appropriate workup. Any method of reduction should always be Friedlander J, Mamula P: Gastrointestinal hemorrhage. To confrm the diagnosis, breastfeeding may be discontinued for Jaundice is the yellow discoloration of skin, sclerae, and other tis 24-48 hours to observe whether a decrease in bilirubin level sues caused by the deposition of bilirubin. Incompatibil from the deposition of unconjugated (indirect) bilirubin in the ity of the Rh factor causes the most severe disease in progressive basal ganglia and brainstem nuclei. Although most cases of neonatal jaundice are physiologic, 1 a careful history and physical examination are necessary to Extravascular blood results in increased bilirubin pro 9 rule out more serious disorders. Other condi syndrome) will increase enterohepatic circulation of bilirubin, tions resulting in a delayed passage of meconium (Hirschsprung contributing to indirect hyperbilirubinemia and jaundice. Prematurity is a risk factor for hyperbilirubinemia that is Prolonged indirect hyperbilirubinemia may be the earli 11 ofen compounded by delayed enteral feeds, parenteral nutri est clinical manifestation of congenital hypothyroidism tion, and perinatal insults due to hypoxia and acidosis. Breast-fed infants tend to have Oxytocin, excess vitamin K in premature infants, some higher and more prolonged unconjugated bilirubin levels. History of acholic hours of life, known blood group incompatibility or hemolytic (clay colored) stools supports an obstructive cause. Elevation of disease, sibling who required phototherapy, cephalohematoma, serum transaminases is caused by intrinsic hepatocellular disease. With severe disease there may be impaired synthetic function causing hypoalbuminemia and a prolonged prothrombin time Nearly all newborns experience some rise in serum biliru 4 that does not correct with vitamin K. A congenital infection is suggested by intrauterine growth 14 Levels higher than those used in the defnition may occur retardation, microcephaly, and ophthalmologic abnormali. Wilson disease, an autosomal recessive disorder of copper 20 Biliary atresia is the most common cause of neonatal cho metabolism, presents in the preadolescent or adolescent age 16 lestasis and should be considered in children with conju group. Diagnosis is by low serum ceruloplasmin level, high an ultrasound to exclude other anatomic abnormalities includ urinary copper excretion, and increased hepatic copper level on ing choledochal cyst. Include a travel history, sexual gens, androgens), isoniazid, pemoline, and antineoplastics. Other causes include Brumbaugh D, Mack C: Conjugated hyperbilirubinemia in children, Pediatr lymphoproliferative disorders, systemic lupus erythematosus, Rev 33:291?302, 2012. Liver function is better as sessed by serum albumin and prothrombin time because they rely on the synthetic function of the liver. Infammatory bowel disease can be associated with hepa 3 tobiliary disease through a variety of mechanisms. Tese The presence of a palpable liver does not always indicate include autoimmune (autoimmune hepatitis), infammatory hepatomegaly. Ask about episodic brucellosis, tularemia, syphilis, Lyme disease, leptospirosis, Rocky vomiting, associated neurologic changes, travel, and drug or Mountain spotted fever, Q fever, tuberculosis, and actinomycosis. Metabolic disease is suggested by symptoms Fitz-Hugh?Curtis syndrome is a perihepatitis associated with pel of failure to thrive, vomiting, loss of developmental mile vic infammatory disease due to Neisseria gonorrhoeae or Chla stones, new seizures, or hypotonia. A 6 should be suspected in infants with hepatomegaly, hypotonia, family history of hepatic, neurologic, and psychiatric symp and loss of developmental milestones. Diagnosis is apy, other medication and toxins, malnutrition, and obesity are typically made early in life owing to a characteristic phenotype, also risk factors. Ascites and tender hepatomegaly are common presenting 12 Wilson disease is in the diferential diagnosis of acute symptoms of hepatic venous outfow obstruction. Kayser-Fleischer transaminases and bilirubin levels are minimally afected rings and neurologic symptoms. Sudden spleno megaly in a child with sickle cell disease suggests acute splenic In children, a palpable spleen may or may not be enlarged, be sequestration, a life-threatening condition. The abdominal ex cause the volume of the spleen may be relatively larger com amination should include attention to the liver and the possibility pared with the volume of the abdomen. Up to 15% of teristic notch on the medial or inferior border of the spleen may newborns, 10% of children, and 5% of adolescents have palpa help identify it, although other nodular masses may be present. A careful H and P will usually suggest stretched acutely, such as in an acute infection or hemolysis. Examples of other infections that may cause splenomegaly 2 A neonatal history of an umbilical catheter is a risk factor include spirochetal, rickettsial, parasitic, fungal, mycobac 1 for portal vein thrombosis and subsequent venous obstruc terial, and protozoal. Pulmonary hyperinfation due to asthma, bronchiolitis, or 7 12 It may be seen in congenital spherocytosis or other congeni a pneumothorax may cause splenic displacement. It is the preferred diagnostic test in neonates and is also appropriate in older Abdominal masses represent a varied group of entities, many of children. In male infants, posterior urethral valves For infants, a perinatal and birth history may reveal risk 1 are the most common cause of hydronephrosis. Malignant cites must be distinguished from abdominal distention due to a hepatic tumors include hepatoblastoma and hepatocellular mass. The fuid shifs with movement of the Wilms tumor is the second most common malignancy in patient and causes a percussion wave or shifing dullness. Wet saline mount of vaginal secretions with microscopy, including use of potassium hydroxide, and Gram stain can be used to detect Dysuria is pain or burning occurring with urination. Constipation, not being circumcised, mydia, herpes simplex, Trichomonas vaginalis). Dark or tea-colored urine may in Nonspecifc urethritis is ofen seen in premenarchal girls dicate hematuria. A history of penile or vaginal discharge as well 6 and is associated with poor hygiene, tight ?nonbreathing as sexual abuse should be elicited. Urethral prolapse method, correlates with infection, particularly in an older child. Bleed Dipstick methods test for leukocyte esterase (an enzyme present ing and dysuria are common. Sexual abuse is ofen associated with rectal or vaginal casts, when present, are associated with upper tract infections. In 9 circumcised boys, it may result from recurrent meatal in In older children, pyelonephritis may be clinically difer 3 fammation from moist diapers. Trauma, hypospadias repair, entiated from cystitis by the presence of systemic features catheterization, and balanitis xerotica obliterans are other causes. Phimosis is when the foreskin may be nonspecifc, with fever and other symptoms present in cannot be retracted because of scarring or narrowing of the pre upper or lower tract disease. Paraphimosis is the also show pyelonephritis but is not as sensitive; however, it is incarceration of the prepuce behind the glans, ofen afer forcible adequate to detect obstructive uropathy or high-grade refux retraction of the foreskin. Balanitis is an infammation of the pre that may be associated with pyelonephritis. A careful neuro Chapter 31 logic examination should be included, assessing strength, tone, sensation and refexes of the lower extremities, and anal wink. The voiding cystourethrogram demonstrates a trabeculated bladder with a ?Christmas tree or ?pine cone Enuresis is urinary incontinence at an age when most children appearance. Secondary enuresis refers to a child cially obese or preschool-aged girls who do not open the labia who was successfully toilet trained for at least 3 to 6 months and when voiding, there may be ?refux of the urine into the va becomes incontinent once again. Some girls who have postvoid (new sibling, school trauma, physical or sexual abuse). Urethral obstruction may appear as abnormal urinary symp 6 It is most important to distinguish between monosymp toms such as dribbling, poor stream, needing to push, or 1 tomatic nocturnal enuresis (which is usually benign) and weak thin stream. Chil urethritis) or trauma (traumatic catheterization, urethral foreign dren with overactive bladder (pediatric unstable bladder) may body. Hinman syndrome (detrusor-sphincter dyssynergia) is enuresis associated with giggling, laughing, coughing, strain an extreme form of this in a child without neurologic abnor ing, or physical activity may indicate the cause.

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